Nixel 512

Fully differential 512 channel neural recording IC designed for 2024

The Nixel 512 chip is a low-noise and low-power mixed-signal programmable neural recording ASIC with 512 electrodes and 16-bit data path. Its uniform array of 256 purpose built active neural recording elements, called nixels, enables differential recording of neural signals with minimal noise.

With high recording density, adjustable controls, and simultaneous spike and local field potential recording, the Nixel 512 chip is tailored to meet the needs of any design, and is especially well suited for neural recording applications. Containing circuitry to record from 512 electrodes with ultimate flexibility in a footprint merely 16 mm2, the Nixel 512 chip offers unparalleled precision and performance for next-generation technologies.

Photograph of the Nixel 512 chip isolated from its background.

Product Features

Chip Architecture

Electrodes are grouped in 4 identical panels, each of which is composed of 128 electrodes recorded differentially using 64 nixels.

Neural Recording

A Nixel is a self-contained neural recording and signal processing element that can be placed on a silicon chip and paired with one or two neurons.

Nixel Features
  • 256 user configurable recording channels
  • Input referred noise: 27-4.5 µV rms
  • Gain: 13-200 V/V
  • High- and low-pass corners
Operating Modes
  • Default Mode
  • High-Resolution Mode
  • Ultra-High-Resolution Mode
Packaging
  • 4.0 mm x 4.0 mm
  • 28 Rows x 26 Columns of Cu-bumps
  • Uniform pitch of 140 μm in both X and Y directions
Nixels and Pixels

Introducing Science's Chip Families for Neural Recording And Stimulation

Learn more

An artistically lit extreme closeup of the rounded copper bumps on the back of a Science Chip. Each bump reflects red light from the left and blue light from the right.
Two integrated circuit designers working at a probe station in a brightly lit cleanroom.

Collaborate with Science Corporation for access to our world-class neural engineering technology

Science Corporation provides Nixel 512 chips to select academic, research, and commercial collaborators. If you have an interesting application for our technology in neuroscience or beyond, learn more about collaborating with Science Corporation.

Collaborate with Science

Documentation

Explore our datasheets and guides for using Nixel 512 for your own experimental setups

Technical documentation

The Science Ecosystem

Software

Intuitive and comprehensive suite of tools to design, program, and run neuroscience experiments.

Nexus Python Library TS Library C++ Library
Software
Hardware
Synapse

Headstages

Electronics that process, store, and transmit signals between probes and the network.

SciFi
Wearables

Probes

Tissue-contacting elements designed for high precision detection and stimulation of neural signals.

Dev Kit
Thin Film Axon Silicon Axon PRIMA Biohybrid Chips

Fabrication

Manufacturing, assembly and packaging of micro scale MEMS and IC devices.

Science Foundry
Your Fab