Axon Probes

Active probes for highly scalable neural engineering built with our Foundry processes and Nixel and Pixel ASICs

Plug-and-play support for thousands of electrodes or microLEDs in a huge range of possible configurations.

Coming Soon Documentation

Fully assembled custom active probes with up to thousands of electrodes or microLEDs, designed to work with Science headstages

Build your probe with Science ASICs: Nixel 512 for electrical recording and Pixel 2K or 16K for optical stimulation, assembled onto either a flexible or rigid substrate designed to reach your anatomical targets. Axon probes enable closed-loop neural stimulation and recording for next generation neuroscience applications.

A block diagram of Axon probes shows the probe receiving analog neural signals and outputting µLED control signals all whilst communicating with a SciFi headstage via USB. The interior of the Axon probe shows Science neural recording ICs sending digitized neural signals to an FPGA which sends digital stimulation frames to Science optogenetic stimulation ICs. A legend at the bottom calls out 'Up to 512 electrodes per IC' and 'Up to 16k µLED per IC'.

One platform, infinite layouts

By adjusting the design parameters like materials and the placement and count of electrodes and LEDs, you can create the exact Axon probe for your work.

  • Thin Film Probes

    Built with layers of polyimide to create flexible structures, Thin Film Axon probes enable a wide range of 3D geometries and surface contact patterns.

  • Silicon Probes Coming Soon

    Built on silicon to create rigid shanks and enable very dense wiring, the Silicon Axon probes are designed for high-density recording and stimulation.

Three SciFi headstages sit next to one another: one flexible, one rigid with a well, and one rigid without a well.

Probe library

Our probes are cataloged according to their quantity of recording and stimulating ICs to make it easier than ever to find the probe configuration that is right for you.

Browse

Find a probe layout that works with your application.

Customize

Download and modify layouts to meet your specific needs.

Reference

Get started with our Standard Technology documentation.

A graphic showing a stack of GDS file screenshots represents a library of probe designs.
A microfabrication engineer works with an intricate sputterer machine.

Built with Science Foundry and our Standard Technology

Axon Probes are produced by Science Foundry in our North Carolina microfabrication facility with our Two Layer Thin Film Electronics Standard Technology. Developed for neural interface devices, our TFE processes can be customized to your unique applications.

Experienced

Our Foundry has been producing innovative MEMS devices since 1999.

Adaptable

Axon Probes are produced with dedicated runs, giving you more process control.

Documented

In-depth documentation is available for all our standard technologies.

Documentation

Explore our datasheets and guides for using Axon Probes for your own experimental setups

Technical documentation

The Science Ecosystem

Software

Intuitive and comprehensive suite of tools to design, program, and run neuroscience experiments.

Nexus Python Library TS Library C++ Library
Software
Hardware
Synapse

Headstages

Electronics that process, store, and transmit signals between probes and the network.

SciFi
Wearables

Probes

Tissue-contacting elements designed for high precision detection and stimulation of neural signals.

Dev Kit
Thin Film Axon Silicon Axon PRIMA Biohybrid Chips

Fabrication

Manufacturing, assembly and packaging of micro scale MEMS and IC devices.

Science Foundry
Your Fab